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FOLATE POLYGLUTAMATES
Descriptors Found:
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DeCS
Descriptor
English
:
Pteroylpolyglutamic Acids
Descriptor
Spanish
:
Ácidos Pteroilpoliglutámicos
Descriptor
Portuguese
:
Ácidos Pteroilpoliglutâmicos
Synonyms
English
:
Folate Polyglutamates
Polyglutamate Folates
Tree Number:
D03.438.733.631.400.600
Definition
English
:
Derivatives of
folic acid
(pteroylglutamic acid). In gamma-glutamyl linkage they are found in many
tissues
. They are converted to
folic acid
by the action of pteroylpolyglutamate hydrolase or synthesized from
folic acid
by the action of folate polyglutamate synthetase. Synthetic
pteroylpolyglutamic acids
, which are in alpha-glutamyl linkage, are active in
bacterial growth
assays.
Indexing Annotation
English
:
deficiency: coordinate
PTEROYLPOLYGLUTAMIC ACIDS
/defic (IM) with
FOLIC ACID DEFICIENCY
(IM)
Pharmacological Action:
Vitamin B Complex
History Note
English
:
91(79); was see under FOLIC ACID 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
27777
Unique Identifier:
D011624
Occurrence in VHL
:
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DeCS
CID-10
SciELO
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